FeCl3-catalysed Zn-mediated allylation of cyclic enol ethers in water

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Iridium-catalyzed enantioselective allylation of silyl enol ethers derived from ketones and α,β-unsaturated ketones.

The unified Ir-catalyzed enantioselective allylic substitution reactions of silyl enol ethers derived from ketones and α,β-unsaturated ketones with branched, racemic allylic alcohols are described. This transformation is catalyzed by the Carreira system and proceeds without fluoride, and with high ee and b : l ratio. The synthetic utility of this method was illustrated by the concise enantiosel...

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ژورنال

عنوان ژورنال: Journal of Chemical Sciences

سال: 2012

ISSN: 0974-3626,0973-7103

DOI: 10.1007/s12039-011-0209-x